Hi,
Don't know it its the best way or not, but I brought my PV wire into the backup camera housing at the back -- no holes in the roof.
Some pictures here:
http://www.buildagreenrv.com/our-co...romaster-van-conversion-solar-panel-mounting/
Down toward the bottom of the page shows the wiring through the camera housing.
If you have not already purchased the PV panels, I'd consider getting one larger panel (you can probably get over 350 watts in one panel these days) -- this would simplify the wiring and eliminate the need for a combiner box on the roof. Not a big deal either way, but something to think about. If you go with one panel, the voltage will be higher which means less voltage drop and smaller wires, but also means you need a charge controller that will handle the higher voltage.
Gary