Engine Knock?

My 2014 2500 3.6L with 161K on it has developed what seems to be a engine knock. Am I screwed?

I recently drove the van across country to Utah and after a few weeks of living here I started noticing the sound.

I have not done the oil since arriving but changed it a few days before our trip across. The van seems to run fine overall but sounds awful. The noise seems to dissipate at speed. I do have 2 codes, a P0420 - Catalyst system below threshold Bank 1 and P0430 -Catalyst efficiency bank 2.

I have not been able to diagnose if there is an exhaust leak due to the recent weather out here but it seems like it could be more than a minor issue.

link to video filmed today.